Trial intelligence / Profile preview

Gemcitabine and Abraxane in Second Line Metastatic Pancreatic Cancer

NCT02242409Phase 2

Key facts

Status
Terminated
Start
Sep 2014
Primary completion
Dec 2016
Countries
1
Sponsor
Georgetown University
Modality
Polymer-based Nanoparticles, Small Molecules
Conditions
pancreatic cancer (PC)
01

Overview

Phase 2, open-label, single-arm trial of nab-paclitaxel in pancreatic cancer (PC), sponsored by Georgetown University. Primary endpoint: 4 month progression free survival. Started Sep 2014; status: terminated.

02

Design

1 arm
Study design
Non-randomizedOpen-label
  • Gemcitabine/abraxane

    Gemcitabine and Abraxane combination therapy

03

Who it enrols

Patients with histologically confirmed metastatic adenocarcinoma of the pancreas who have progressed on first-line non-gemcitabine based therapy.

04

Endpoints

Primary

  • 4 month progression free survival

Secondary

  • Disease control rate

  • Progression Free Survival

  • Overall Survival

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