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Estradiol effects on reward system in perimenopausal depression

NCT02255175Phase 4Completed

Sponsor
University of North Carolina at Chapel Hill
Start
Oct 2015
Primary completion
Oct 2018
Modality
Hormone, Biologic
Countries
1
01

Overview

Phase 4, open-label trial of estradiol in perimenopausal depression (2 arms), sponsored by University of North Carolina at Chapel Hill. Primary endpoints: Caudate Signal Intensity in Response to Reward During the MID fMRI Task, Nucleus Accumbens (NAcc) Signal Intensity in Response to Reward During the MID fMRI Task and 1 more. Started Oct 2015; status: completed.

02

Drugs

estradiol
03

Conditions

perimenopausal depression

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