Trial intelligence / Profile preview

Nicotine effects on brain reward pathways in MDD

NCT02346539Phase 1Completed

Sponsor
McLean Hospital
Start
Feb 2015
Primary completion
Nov 2017
Modality
Polymer-based Nanoparticles, Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in major depressive disorder (MDD) comparing Nicotine with Placebo (2 arms). Primary endpoint: Change from Placebo in functional magnetic resonance imaging (fMRI) BOLD Response at 2 weeks. Started Feb 2015; status: completed.

02

Drugs

nicotine polacrilex
03

Conditions

major depressive disorder (MDD)

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