Trial intelligence / Profile preview

Afuresertib with Enzalutamide or Abiraterone in mCRPC

NCT02380313Phase 1Withdrawn

Sponsor
GSK
Start
Oct 2015
Primary completion
May 2017
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of afuresertib in metastatic castration-resistant prostate cancer (mCRPC) (2 arms), sponsored by GSK. Primary endpoints: Number of participants with adverse events, serious adverse events and dose limiting toxicities up to 6 months, Change from baseline in composite of laboratory parameters up to 6 months and 4 more. Planned start Oct 2015; status: withdrawn.

02

Drugs

afuresertib
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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