Trial intelligence / Profile preview

AAV2hAQP1 Gene Therapy for Radiation-Induced Parotid Salivary Hypofunction

NCT02446249Phase 1Completed

Sponsor
MeiraGTx
Start
May 2015
Primary completion
Aug 2026
Modality
Gene Editing, Gene Silencing, Gene Addition/Replacement
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of AAV-AQP1 in radiation-induced xerostomia and salivary hypofunction, sponsored by MeiraGTx. Primary endpoint: Safety of vector at 36 months. Started May 2015; status: completed.

02

Drugs

AAV-AQP1
03

Conditions

radiation-induced xerostomiasalivary hypofunction

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