Trial intelligence / Profile preview

Givosiran in Acute Intermittent Porphyria

NCT02452372Phase 1Completed

Sponsor
Alnylam Pharmaceuticals
Start
May 2015
Primary completion
Sep 2017
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
3
01

Overview

Phase 1, randomised, single-blind trial in acute intermittent porphyria (AIP) comparing givosiran (ALN-AS1) with Placebo (2 arms). Primary endpoint: Safety and Tolerability (AEs, SAEs, Discontinuations) at Day 168. Started May 2015; status: completed.

02

Drugs

givosiran
03

Conditions

acute intermittent porphyria (AIP)

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