Trial intelligence / Profile preview

Ondansetron effects on brain function in healthy adults

NCT02460341Phase 1Completed

Sponsor
Icahn School of Medicine at Mount Sinai
Start
Aug 2015
Primary completion
Feb 2017
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of ondansetron in obsessive compulsive disorder (OCD) and Tourette syndrome (TS) (3 cohorts), sponsored by Icahn School of Medicine at Mount Sinai. Primary endpoint: BOLD signal in the insula and somatosensory cortex measured by fMRI at 1 week. Started Aug 2015; status: completed.

02

Drugs

ondansetron
03

Conditions

obsessive compulsive disorder (OCD)Tourette syndrome (TS)

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