Trial intelligence / Profile preview

SOPHIA: Margetuximab vs Trastuzumab in HER2+ Metastatic Breast Cancer

NCT02492711Phase 3Completed

Sponsor
MacroGenics
Start
Aug 2015
Primary completion
Aug 2021
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Countries
18
01

Overview

Phase 3, randomised, open-label trial of margetuximab in breast cancer (3 arms), sponsored by MacroGenics. Primary endpoints: Progression-free Survival at 5 months, Overall Survival at 21 months and 1 more. Started Aug 2015; status: completed.

02

Drugs

margetuximab
03

Conditions

breast cancer

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