Trial intelligence / Profile preview

MUC16ecto-targeted CAR T Cells in Recurrent MUC16ecto+ Solid Tumors

NCT02498912Phase 1Active, not recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Aug 2015
Primary completion
Aug 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of 4H11-28z + fIL-12 in ovarian cancer, primary peritoneal carcinoma (PPC) and fallopian tube carcinoma (PFTC), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Maximum Tolerated Dose at 2 years. Started Aug 2015; status: active, not recruiting.

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Drugs

4H11-28z + fIL-12
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Conditions

ovarian cancerprimary peritoneal carcinoma (PPC)fallopian tube carcinoma (PFTC)

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