Trial intelligence / Profile preview

Romidepsin in T-Cell Malignancies Allo-SCT

NCT02512497Phase 1Completed

Sponsor
The Ohio State University Comprehensive Cancer Center – James Cancer Hospital
Start
Dec 2017
Primary completion
Oct 2023
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of romidepsin in cutaneous T-cell lymphoma (CTCL), T-cell prolymphocytic leukemia (T-PLL), T-cell large granular lymphocytic leukemia and 2 more, sponsored by The Ohio State University Comprehensive Cancer Center – James Cancer Hospital. Primary endpoints: Toxicity of Romidepsin with Busulfan and Fludarabine Conditioning Therapy at 30 days and Efficacy of Romidepsin with Busulfan and Fludarabine Conditioning Therapy. Started Dec 2017; status: completed.

02

Drugs

romidepsin
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Conditions

cutaneous T-cell lymphoma (CTCL)T-cell prolymphocytic leukemia (T-PLL)T-cell large granular lymphocytic leukemiaT-cell lymphoblastic leukemia/lymphoma (T-LBL/ALL)peripheral T-cell lymphoma (PTCL)

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