Trial intelligence / Profile preview

BISCAY: Biomarker-Directed Study in MIBC

NCT02546661Phase 1Active, not recruiting

Sponsor
AstraZeneca
Start
Dec 2016
Primary completion
Mar 2020
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
5
01

Overview

Phase 1, randomised, open-label trial of durvalumab, fexagratinib, olaparib, adavosertib, vistusertib and 2 more in muscle-invasive bladder cancer (MIBC) (8 arms), sponsored by AstraZeneca. Primary endpoints: Adverse Events, Change from baseline in clinical chemistry parameters and 1 more. Started Dec 2016; status: active, not recruiting.

02

Drugs

durvalumabfexagratinibolaparibadavosertibvistusertib
03

Conditions

muscle-invasive bladder cancer (MIBC)

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