Trial intelligence / Profile preview

GBT440 DDI Study in Healthy Subjects

NCT02567682Phase 1Completed

Sponsor
Global Blood Therapeutics
Start
Sep 2015
Primary completion
May 2016
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of voxelotor in sickle cell disease (SCD), sponsored by Global Blood Therapeutics. Primary endpoints: Peak plasma concentration for caffeine, S-warfarin, omeprazole, and midazolam, Area under the plasma concentration-time curve from time 0 to the time of the last quantifiable concentration for caffeine, S-warfarin, omeprazole, and midazolam and 1 more. Started Sep 2015; status: completed.

02

Drugs

voxelotor
03

Conditions

sickle cell disease (SCD)

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