Trial intelligence / Profile preview

Toca 511 and Toca FC in Advanced Solid Tumors or Lymphoma

NCT02576665Phase 1Terminated

Sponsor
Tocagen
Start
Jul 2016
Primary completion
May 2019
Modality
Gene Editing, Gene Silencing, Oncolytic Viruses
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of vocimagene amiretrorepvec in colorectal cancer (CRC), triple-negative breast cancer (TNBC), pancreatic cancer (PC) and 9 more, sponsored by Tocagen. Primary endpoint: Changes from baseline in immune activity in tumor and peripheral blood. Started Jul 2016; status: terminated.

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Drugs

vocimagene amiretrorepvec
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Conditions

colorectal cancer (CRC)triple-negative breast cancer (TNBC)pancreatic cancer (PC)non-small cell lung cancer (NSCLC)head and neck cancer (HNC)

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