Trial intelligence / Profile preview

MLN9708 with Induction and Consolidation Chemotherapy in Older Adults with AML

NCT02582359Phase 1Completed

Sponsor
Massachusetts General Hospital
Start
Jan 2016
Primary completion
Apr 2022
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of ixazomib in acute myeloid leukemia (AML), sponsored by Massachusetts General Hospital. Primary endpoints: Maximum Tolerated Dose / Recommended Phase 2 Dose of MLN9708 in combination with induction chemotherapy at 1 year and Maximum Tolerated Dose / Recommended Phase 2 Dose of MLN9708 with combination with consolidation chemotherapy at 1 year. Started Jan 2016; status: completed.

02

Drugs

ixazomib
03

Conditions

acute myeloid leukemia (AML)

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