Trial intelligence / Profile preview

Pembrolizumab and Palliative Radiotherapy in Thoracic Tumours

NCT02587455Phase 1Completed

Sponsor
Royal Marsden NHS Foundation Trust
Start
Jun 2016
Primary completion
Aug 2021
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 1, open-label trial of pembrolizumab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Royal Marsden NHS Foundation Trust. Primary endpoints: Toxicity Rate of Dose Limiting Toxicities (DLTs) Assessed by CTCAEv4 and Maximum Tolerated Dose (MTD) of Pembrolizumab That Can be Safely Combined With Radiotherapy (RT). Started Jun 2016; status: completed.

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Drugs

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Conditions

non-small cell lung cancer (NSCLC)

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