Trial intelligence / Profile preview

Odronextamab and Cemiplimab in B-Cell Malignancies (CLIO-1)

NCT02651662Phase 1Completed

Sponsor
Regeneron Pharmaceuticals
Start
Jan 2016
Primary completion
Apr 2026
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
6
01

Overview

Phase 1, open-label trial of odronextamab and cemiplimab in B cell lymphoma (2 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoints: Incidence of dose limiting toxicities at 28 days, Incidence of treatment emergent adverse events at 18 months and 3 more. Started Jan 2016; status: completed.

02

Drugs

odronextamabcemiplimab
03

Conditions

B cell lymphoma

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