Trial intelligence / Profile preview

HVTN 112: HIV-1 pDNA and rVSV Prime-Boost Vaccine Trial

NCT02654080Phase 1Completed

Sponsor
National Institute of Allergy and Infectious Diseases
Start
Mar 2016
Primary completion
Aug 2017
Modality
Gene Editing, Viral Vector Vaccines, Gene Silencing
Countries
1
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Overview

Phase 1, randomised, double-blind trial of HIV-1 nef/tat/vif, env pDNA and rVSV HIV envC in human immunodeficiency virus infection (HIV) (2 arms), sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoints: Frequency of local injection/EP site and systemic reactogenicity signs and symptoms at Month 15, Severity of local injection/EP site and systemic reactogenicity signs and symptoms at Month 15 and 4 more. Started Mar 2016; status: completed.

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Drugs

HIV-1 nef/tat/vif, env pDNArVSV HIV envC
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Conditions

human immunodeficiency virus infection (HIV)

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