Trial intelligence / Profile preview

Duvortuxizumab + Ibrutinib in B-Cell Malignancies

NCT02743546Phase 1Withdrawn

Sponsor
Janssen Pharmaceutical
Start
Jul 2016
Primary completion
Sep 2018
Modality
Antibody Conjugates, Bispecific Antibodies, Monoclonal Antibodies
01

Overview

Phase 1, open-label trial of duvortuxizumab in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), mantle cell lymphoma (MCL) and 1 more (5 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Number of Participants With Dose Limiting Toxicity at 9 months, Number of Participants With Adverse Events at 2 years and 2 more. Planned start Jul 2016; status: withdrawn.

02

Drugs

duvortuxizumab
03

Conditions

diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)mantle cell lymphoma (MCL)chronic lymphocytic leukemia (CLL)

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