Pharmacokinetics of BI 425809 With Cytochrome P450 and P-gp Substrates in Healthy Male Subjects

Phase 1, open-label, single-arm trial of iclepertin, sponsored by Boehringer Ingelheim. Primary endpoints: Area Under the Concentration-time Curve of Midazolam in Plasma Over the Time Interval From 0 to the Last Quantifiable Data Point at 24 hours, Area Under the Concentration-time Curve of Omeprazole in Plasma Over the Time Interval From 0 to the Last Quantifiable Data Point at 24 hours and 6 more. Started Sep 2015; status: completed.