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ADME Variability in Five Human Populations
NCT02789527Completed
- Start
- Nov 2015
- Primary completion
- Apr 2017
- Modality
- Small Molecules
- Countries
- 4
01
Overview
Open-label trial of caffeine, bupropion, flurbiprofen, omeprazole, dextromethorphan and 2 more (4 arms). Primary endpoints: Frequencies of genotypes and haplotypes of genes involved in drug responses at 2 years and Activities of 6 cytochrome P450 enzymes and P-gp at 2 years. Started Nov 2015; status: completed.
02
Drugs
caffeinebupropionflurbiprofenomeprazoledextromethorphan
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