Trial intelligence / Profile preview

(+)-Alpha-Dihydrotetrabenazine Phase I

NCT02844179Phase 1Completed

Start
Jul 2016
Primary completion
Jun 2017
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of dihydrotetrabenazine in Huntington's disease (HD). Primary endpoints: VMAT2 occupancy by HTBZ determined by positron emission tomography (PET) scanning at 60 minutes and Safety and Tolerability of single oral doses of HTBZ at 1 day. Started Jul 2016; status: completed.

02

Drugs

dihydrotetrabenazine
03

Conditions

Huntington's disease (HD)

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