Trial intelligence / Profile preview

EVALUATE-HF: Sacubitril/Valsartan vs Enalapril on Aortic Stiffness in HFrEF

NCT02874794Phase 4Completed

Sponsor
Novartis
Start
Aug 2016
Primary completion
Dec 2018
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial of sacubitril + valsartan in heart failure with reduced ejection fraction (HFrEF) (2 arms), sponsored by Novartis. Primary endpoint: Change From Baseline in Aortic Characteristic Impedance (Zc) at 12 weeks. Started Aug 2016; status: completed.

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Drugs

sacubitril + valsartan
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Conditions

heart failure with reduced ejection fraction (HFrEF)

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