Trial intelligence / Profile preview

Universal Donor NK Cell Therapy + ALT-803 in Cancer

NCT02890758Phase 1Completed

Start
May 2018
Primary completion
Jun 2021
Modality
Cytokines & Interferons, Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 1, open-label trial of Natural Killer Cells and nogapendekin alfa inbakicept in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), acute lymphoblastic leukemia (ALL) and 11 more (2 arms). Primary endpoints: Maximum Tolerated Dose at 28 days and Number of participants without Graft Versus Host Disease at 28 days. Started May 2018; status: completed.

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Drugs

Natural Killer Cellsnogapendekin alfa inbakicept
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)acute lymphoblastic leukemia (ALL)chronic myeloid leukemia (CML)chronic lymphocytic leukemia (CLL)

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