Trial intelligence / Profile preview

Intraventricular Methotrexate and Etoposide for Recurrent Posterior Fossa Tumors

NCT02905110Phase 1Completed

Sponsor
UTHealth Houston
Start
Oct 2017
Primary completion
Mar 2022
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 1, open-label, single-arm trial of methotrexate and etoposide in medulloblastoma, ependymoma and Atypical teratoid rhabdoid tumor (ATRT), sponsored by UTHealth Houston. Primary endpoint: Number of patients with grade 3 through grade 5 new neurological adverse events at 4 months. Started Oct 2017; status: completed.

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Drugs

methotrexateetoposide
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Conditions

medulloblastomaependymomaAtypical teratoid rhabdoid tumor (ATRT)

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