Trial intelligence / Profile preview

Mechanisms of Cerebrovascular Control in Metabolic Syndrome

NCT02936687Phase 1Completed

Sponsor
University of Wisconsin–Madison
Start
Jan 2017
Primary completion
Jul 2021
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 1, randomised, single-blind trial of NG-monomethyl-L-arginine and ambrisentan in metabolic syndrome (4 arms), sponsored by University of Wisconsin–Madison. Primary endpoints: Change in cerebrovascular blood flow in response to NOS inhibition and Change in cerebrovascular blood flow in response to ET-1 inhibition. Started Jan 2017; status: completed.

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Drugs

NG-monomethyl-L-arginineambrisentan
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Conditions

metabolic syndrome

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