Trial intelligence / Profile preview

Efficacy of Three ACTs for Uncomplicated Malaria in DRC Children

NCT02940756Phase 4Completed

Sponsor
Ministry of Public Health, Hygiene and Prevention of the Democratic Republic of the Congo
Start
Mar 2017
Primary completion
Jan 2018
Modality
Bivalent/Multivalent Binders, Nucleic Acid-Directed Small Molecules, Orthosteric Ligands
Countries
1
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Overview

Phase 4, randomised, open-label trial in Plasmodium falciparum malaria comparing Artesunate-Amodiaquine, Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine (3 arms). Primary endpoint: PCR-adjusted efficacy at 42 days. Started Mar 2017; status: completed.

02

Drugs

artesunate + amodiaquineartemether + lumefantrinedihydroartemisinin + piperaquine
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Conditions

Plasmodium falciparum malaria

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