Trial intelligence / Profile preview

CD45RA-depleted T-memory cells for infection prevention post-HSCT

NCT02942173Phase 3Completed

Sponsor
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology
Start
Oct 2016
Primary completion
Aug 2019
Modality
Adoptive Cell Transfer
Countries
1
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Overview

Phase 3, randomised, open-label trial of CD45RA depleted donor lymphocyte infusion in cytomegalovirus infection (CMV) (2 arms), sponsored by Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. Primary endpoints: Cumulative incidence of the probability of CMV-reactivation at 120 days and Cumulative incidence of acute GVHD grade II-IV at 150 days. Started Oct 2016; status: completed.

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Drugs

CD45RA depleted donor lymphocyte infusion
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Conditions

cytomegalovirus infection (CMV)

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