Trial intelligence / Profile preview

CNS10-NPC-GDNF in ALS

NCT02943850Phase 1Completed

Sponsor
Cedars-Sinai Medical Center
Start
Apr 2017
Primary completion
Oct 2019
Modality
Gene Editing, Gene Silencing, Cell Therapies
Countries
1
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Overview

Phase 1, single-blind, single-arm trial of CNS10-NPC-GDNF in amyotrophic lateral sclerosis (ALS), sponsored by Cedars-Sinai Medical Center. Primary endpoint: Safety evaluated by Adverse Events and Serious Adverse Events, post-operative MRI, and clinical laboratory assessments at 12 months. Started Apr 2017; status: completed.

02

Drugs

CNS10-NPC-GDNF
03

Conditions

amyotrophic lateral sclerosis (ALS)

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