Trial intelligence / Profile preview

Neurovascular Regulation During Exercise in Chronic Kidney Disease

NCT02947750Phase 2Recruiting

Sponsor
Emory University
Start
Oct 2016
Primary completion
Apr 2027
Modality
Allosteric Modulators, Metabolically Activated Prodrugs
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of sapropterin in chronic kidney disease (CKD) (6 arms), sponsored by Emory University. Primary endpoints: Change in functional sympatholysis at 12 weeks, Change in vascular alpha 1 adrenergic responsiveness at 12 weeks and 1 more. Started Oct 2016; status: recruiting.

02

Drugs

sapropterin
03

Conditions

chronic kidney disease (CKD)

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