Trial intelligence / Profile preview

OPTIPRIM-2: Dolutegravir vs Darunavir/Cobicistat in Primary HIV-1 Infection

NCT02987530Phase 3Completed

Sponsor
ANRS
Start
Apr 2017
Primary completion
Jul 2019
Modality
Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in human immunodeficiency virus type 1 infection (HIV-1) comparing Dolutegravir + Emtricitabine/Tenofovir with Darunavir/Cobicistat + Emtricitabine/Ténofovir (2 arms). Primary endpoint: HIV-DNA levels in the peripheral blood mononuclear cell (PBMC) at 48 weeks. Started Apr 2017; status: completed.

02

Drugs

dolutegravirdarunavir + cobicistat
03

Conditions

human immunodeficiency virus type 1 infection (HIV-1)

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