Trial intelligence / Profile preview

KEYNOTE-523: Lenvatinib plus Pembrolizumab in Selected Solid Tumors

NCT03006887Phase 1Completed

Sponsor
Eisai Co., Ltd.
Start
Jan 2017
Primary completion
Apr 2020
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of lenvatinib and pembrolizumab in non-small cell lung cancer (NSCLC), clear cell renal cell carcinoma (ccRCC), endometrial carcinoma and 3 more, sponsored by Eisai Co., Ltd. Primary endpoints: Number of Participants With Treatment-emergent Adverse Events and Serious Adverse Events and Number of Participants With Dose-limiting Toxicities. Started Jan 2017; status: completed.

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Drugs

lenvatinibpembrolizumab
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Conditions

non-small cell lung cancer (NSCLC)clear cell renal cell carcinoma (ccRCC)endometrial carcinomaurothelial carcinoma (UC)squamous cell carcinoma of the head and neck (HNSCC)

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