Trial intelligence / Profile preview

Gene-by-Stress Interactions in Intervention Studies

NCT03011645Phase 1Terminated

Sponsor
Duke University
Start
May 2018
Primary completion
Jan 2020
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM) comparing Ziprasidone, Lorcaserin and Placebo (3 arms). Primary endpoints: Change in peak blood cortisol during the metabolic stress of an OGTT at 3 hours and Change in peak blood cortisol during the metabolic stress of a mental stress test at 3 hours. Started May 2018; status: terminated.

02

Drugs

lorcaserinziprasidone
03

Conditions

cardiovascular diseases (CVD)type 2 diabetes mellitus (T2DM)

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