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Naloxone and Methylnaltrexone on Esophageal Sensitivity
NCT03014843Phase 1Completed
- Sponsor
- UZ Leuven
- Start
- Oct 2013
- Primary completion
- Jan 2014
- Modality
- Orthosteric Ligands
01
Overview
Phase 1, randomised, double-blind trial comparing Naloxone, Methylnaltrexone bromide and Placebo (3 arms). Primary endpoints: Changes in esophageal sensitivity after IV naloxone or IM methylnaltrexone administration (Thermal stimulation), Changes in esophageal sensitivity after IV naloxone or IM methylnaltrexone administration (Mechanical stimulation) and 2 more. Started Oct 2013; status: completed.
02
Drugs
naloxonemethylnaltrexone
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