Trial intelligence / Profile preview

huCART-meso in Mesothelin Expressing Cancers

NCT03054298Phase 1Completed

Sponsor
University of Pennsylvania
Start
Apr 2017
Primary completion
Nov 2023
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label trial of huCART-meso cells in lung adenocarcinoma, ovarian cancer, primary peritoneal carcinoma (PPC) and 3 more (7 cohorts), sponsored by University of Pennsylvania. Primary endpoint: Number of Participants With Treatment-related Adverse Events at 7 years. Started Apr 2017; status: completed.

02

Drugs

huCART-meso cells
03

Conditions

lung adenocarcinomaovarian cancerprimary peritoneal carcinoma (PPC)fallopian tube cancer (PFTC)pleural mesothelioma

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