Trial intelligence / Profile preview

Lorlatinib in ALK-Driven Relapsed or Refractory Neuroblastoma

NCT03107988Phase 1Completed

Sponsor
New Advances in Neuroblastoma Therapy
Start
Sep 2017
Primary completion
Aug 2024
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
4
01

Overview

Phase 1, open-label trial of lorlatinib in neuroblastoma (13 cohorts), sponsored by New Advances in Neuroblastoma Therapy. Primary endpoints: Maximum Tolerated Dose / Recommended Phase 2 Dose at Day 28 and Non-Hematological and Hematological Toxicities. Started Sep 2017; status: completed.

02

Drugs

lorlatinib
03

Conditions

neuroblastoma

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