Trial intelligence / Profile preview

TNO155 Alone and in Combination With EGF816 in Advanced Solid Tumors

NCT03114319Phase 1Terminated

Sponsor
Novartis
Start
May 2017
Primary completion
Jul 2025
Modality
Small Molecules
Countries
9
01

Overview

Phase 1, open-label trial of batoprotafib in non-small cell lung cancer (NSCLC), Esophageal Squamous Cell Carcinoma (ESCC), head and neck squamous cell carcinoma (HNSCC) and 2 more (2 arms), sponsored by Novartis. Primary endpoints: Number of participants with adverse events and serious adverse events up to 5 years, Number of participants with dose limiting toxicities up to 28 days and 2 more. Started May 2017; status: terminated.

02

Drugs

batoprotafib
03

Conditions

non-small cell lung cancer (NSCLC)Esophageal Squamous Cell Carcinoma (ESCC)head and neck squamous cell carcinoma (HNSCC)melanomagastrointestinal stromal tumor (GIST)

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