Trial intelligence / Profile preview

Abbreviated MAPK Targeted Therapy Plus Pembrolizumab in Unresectable or Metastatic Melanoma

NCT03149029Phase 2Active, not recruiting

Sponsor
Massachusetts General Hospital
Start
Nov 2017
Primary completion
Dec 2021
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of pembrolizumab, trametinib and dabrafenib + trametinib in melanoma (2 arms), sponsored by Massachusetts General Hospital. Primary endpoint: Rate of Clinical Benefit at 6 months. Started Nov 2017; status: active, not recruiting.

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Drugs

pembrolizumabtrametinibdabrafenib + trametinib
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Conditions

melanoma

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