Trial intelligence / Profile preview

Palbociclib and Binimetinib in Advanced KRAS Mutant NSCLC

NCT03170206Phase 1Completed

Sponsor
Dana-Farber Cancer Institute
Start
May 2017
Primary completion
Feb 2023
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of palbociclib and binimetinib in non-small cell lung cancer (NSCLC), sponsored by Dana-Farber Cancer Institute. Primary endpoints: Maximum Tolerated Dose at 2 years, Safety and tolerability of Palbocilib and Binimetinib at 2 years and 1 more. Started May 2017; status: completed.

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Drugs

palbociclibbinimetinib
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Conditions

non-small cell lung cancer (NSCLC)

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