Trial intelligence / Profile preview

Safety and Immunogenicity of pDNA HIV Vaccines (p24CE1/2 and p55^gag) with IL-12 Adjuvant in Healthy Adults

NCT03181789Phase 1Completed

Sponsor
National Institute of Allergy and Infectious Diseases
Start
Oct 2017
Primary completion
Oct 2019
Modality
Prophylactic Vaccines, DNA Vaccines
Countries
1
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Overview

Phase 1, randomised trial of p24CE DNA vaccine and p55Gag plasmid DNA vaccine in human immunodeficiency virus infection (HIV) (4 arms), sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoints: Number of Participants Reporting Local Reactogenicity Signs and Symptoms: Pain and/or Tenderness at Month 6, Number of Participants Reporting Local Reactogenicity Signs and Symptoms: Erythema and/or Induration at Month 6 and 11 more. Started Oct 2017; status: completed.

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Drugs

p24CE DNA vaccinep55Gag plasmid DNA vaccine
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Conditions

human immunodeficiency virus infection (HIV)

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