Trial intelligence / Profile preview

Haploidentical NK Cells and Hu14.18-IL2 in Neuroblastoma and Osteosarcoma

NCT03209869Phase 1Withdrawn

Sponsor
University of Wisconsin–Madison
Start
Mar 2018
Primary completion
Sep 2022
Modality
Immunomodulatory ADCs, Fc-Fusion Proteins, Lymphokine-Activated Killer Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of haploidentical natural killer cells and Lorukafusp alfa in neuroblastoma and osteosarcoma (OS), sponsored by University of Wisconsin–Madison. Primary endpoints: Incidence of treatment-emergent adverse events and Incidence of any grade acute or chronic GVHD. Planned start Mar 2018; status: withdrawn.

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Drugs

haploidentical natural killer cellsLorukafusp alfa
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Conditions

neuroblastomaosteosarcoma (OS)

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