Trial intelligence / Profile preview

Nivolumab +/- Ipilimumab with Chemotherapy in Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT03245892Phase 1Completed

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Aug 2017
Primary completion
Dec 2025
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label trial of nivolumab and ipilimumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (2 arms), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoints: Number of patients with dose limiting toxicities with weekly paclitaxel/carboplatin plus nivolumab at 6 weeks and Number of patients with dose limiting toxicities weekly paclitaxel/carboplatin plus nivolumab and ipilimumab at 6 weeks. Started Aug 2017; status: completed.

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Drugs

nivolumabipilimumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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