Trial intelligence / Profile preview

ASP8374 Monotherapy and Combination with Pembrolizumab in Advanced Solid Tumors

NCT03260322Phase 1Completed

Sponsor
Astellas Pharma
Start
Sep 2017
Primary completion
May 2022
Modality
Prophylactic Vaccines, IgG Antibodies, Therapeutic Vaccines
Countries
9
01

Overview

Phase 1, open-label trial of ASP8374 in solid tumor (advanced stage), non-small cell lung cancer (NSCLC), bladder cancer and 4 more (17 arms), sponsored by Astellas Pharma. Primary endpoints: Number of Participants with Dose Limiting Toxicities up to 21 Days, Number of Participants with Treatment Emergent Adverse Events and 11 more. Started Sep 2017; status: completed.

02

Drugs

ASP8374
03

Conditions

solid tumor (advanced stage)non-small cell lung cancer (NSCLC)bladder cancergastric cancer (GC)metastatic castration-resistant prostate cancer (mCRPC)

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