Trial intelligence / Profile preview

Vorinostat augmentation of clozapine in schizophrenia

NCT03263533Phase 1Withdrawn

Sponsor
Virginia Commonwealth University
Start
Apr 2017
Primary completion
Feb 2019
Modality
Covalent Small Molecules, Classical Binding Small Molecules
01

Overview

Phase 1, randomised, double-blind trial in schizophrenia comparing Vorinostat Sequence with Placebo Sequence (2 arms). Primary endpoints: Incidence of Treatment-Emergent Adverse Events at 10 weeks and Change in clinical cognitive symptoms at 10 weeks. Planned start Apr 2017; status: withdrawn.

02

Drugs

vorinostat
03

Conditions

schizophrenia

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