Trial intelligence / Profile preview

Blinatumomab and Ponatinib in Ph+ and/or BCR-ABL+ ALL

NCT03263572Phase 2Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Nov 2017
Primary completion
Nov 2027
Modality
Antibody Conjugates, scFv Fragments, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of blinatumomab and ponatinib in acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Complete molecular response rate at 18 weeks, Overall response rate at 12 weeks and 3 more. Started Nov 2017; status: recruiting.

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Drugs

blinatumomabponatinib
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Conditions

acute lymphoblastic leukemia (ALL)chronic myeloid leukemia (CML)

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