Trial intelligence / Profile preview

Autogene Cevumeran Alone and With Atezolizumab in Advanced Solid Tumors

NCT03289962Phase 1Completed

Sponsor
Genentech
Start
Dec 2017
Primary completion
Jul 2025
Modality
Vaccines & Immunotherapeutics, mRNA Therapeutics
Countries
8
01

Overview

Phase 1, open-label trial of autogene cevumeran in melanoma, non-small cell lung cancer (NSCLC), bladder cancer and 5 more (5 arms), sponsored by Genentech. Primary endpoints: Percentage of Participants with Dose-Limiting Toxicities at 21 days, Maximum Tolerated Dose/Recommended Phase 2 Dose of Autogene Cevumeran at 21 days and 7 more. Started Dec 2017; status: completed.

02

Drugs

autogene cevumeran
03

Conditions

melanomanon-small cell lung cancer (NSCLC)bladder cancercolorectal cancer (CRC)triple-negative breast cancer (TNBC)

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