Trial intelligence / Profile preview

CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS

NCT03291444Phase 1Recruiting

Sponsor
Southern Medical University Zhujiang Hospital
Start
May 2018
Primary completion
Dec 2024
Modality
Whole Cell Cancer Vaccines, Dendritic Cell Vaccines
Countries
1
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Overview

Phase 1, open-label trial of eps8 peptide-specific dendritic cell vaccine and WT1 peptide-pulsed dendritic cell vaccine in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and myelodysplastic syndrome (MDS) (2 arms), sponsored by Southern Medical University Zhujiang Hospital. Primary endpoint: Occurrence of study related adverse events up to 12 months. Started May 2018; status: recruiting.

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Drugs

eps8 peptide-specific dendritic cell vaccineWT1 peptide-pulsed dendritic cell vaccine
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Conditions

acute myeloid leukemia (AML)acute lymphoblastic leukemia (ALL)myelodysplastic syndrome (MDS)

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