Trial intelligence / Profile preview

Dolcanatide Bioactivity in Healthy Volunteers

NCT03300570Phase 1Completed

Sponsor
National Cancer Institute
Start
Jul 2018
Primary completion
Jan 2019
Modality
Recombinant Proteins and Enzymes, Modified Peptides, Native Peptides
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in colorectal cancer (CRC) comparing Dolcanatide with Placebo (2 arms). Primary endpoint: Pharmacological Effect on Cyclic Guanosine Monophosphate (cGMP) Levels at 7 days. Started Jul 2018; status: completed.

02

Drugs

dolcanatide
03

Conditions

colorectal cancer (CRC)

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