Trial intelligence / Profile preview

ARO-AAT in healthy volunteers

NCT03362242Phase 1Completed

Sponsor
Arrowhead Pharmaceuticals
Start
Mar 2018
Primary completion
Oct 2018
Modality
Antisense DNA, Conjugated siRNA, MicroRNA (miRNA)
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in alpha-1 antitrypsin deficiency (AATD) comparing ARO-AAT with Placebo (2 arms). Primary endpoint: Adverse Events Possibly or Probably Related to Treatment at 113 days. Started Mar 2018; status: completed.

02

Drugs

fazirsiran
03

Conditions

alpha-1 antitrypsin deficiency (AATD)

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