Trial intelligence / Profile preview

Febuxostat and Rasburicase on Endothelial Function and Oxidative Stress

NCT03395977Completed

Sponsor
Erasmus Hospital
Start
Jan 2018
Primary completion
Dec 2019
Modality
Small Molecules, Replacement Enzymes
Countries
1
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Overview

Randomised, double-blind trial of febuxostat and rasburicase in endothelial dysfunction, hypertension (HTN) and oxidative stress (4 arms), sponsored by Erasmus Hospital. Primary endpoint: Cutaneous perfusion by Laser Doppler at 24 hours. Started Jan 2018; status: completed.

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Drugs

febuxostatrasburicase
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Conditions

endothelial dysfunctionhypertension (HTN)oxidative stress

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