Trial intelligence / Profile preview

Daratumumab and Ibrutinib for Symptomatic, Treatment-Naive CLL

NCT03447808Phase 1Completed

Start
Aug 2018
Primary completion
May 2026
Modality
Recombinant Proteins and Enzymes, Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of daratumumab and ibrutinib in chronic lymphocytic leukemia (CLL). Primary endpoints: Complete response (CR) + complete response with incomplete marrow recovery (CRi) up to 2 years and Incidence of adverse events up to 2 years. Started Aug 2018; status: completed.

02

Drugs

daratumumabibrutinib
03

Conditions

chronic lymphocytic leukemia (CLL)

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